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Trade Ideas

Global Trade Idea - Gilead Sciences Inc. (GILD US) - BUY

 

By Peet Serfontein & Khumbulani Kunene

We enter a long position with a target price of $155.00 and a stop-loss of $128.00.

Gilead Sciences is a research-based biopharmaceutical company that develops and commercialises innovative therapeutics/medicines for serious and life-threatening diseases. The company's primary areas of focus include HIV, AIDS, liver disease, and serious cardiovascular and respiratory conditions. It has also expanded its operations into oncology, inflammatory diseases and cell therapy through its Kite subsidiary.

The group generates revenue primarily from its portfolio of prescription medicines, supported by continued investment in clinical research, strategic partnerships and acquisitions. Its established HIV franchise remains central to the business, while oncology and inflammation provide important opportunities for longer-term growth and diversification.

Technically, the in-house AI model's forecast supports the profit target and presents an attractive buying opportunity (see the insert on the main chart). This model analyses seven years of historical price and volume data, together with trend, momentum and volatility indicators, to estimate the stock's potential price trajectory across several time horizons. Our proposed $155.00 profit target falls between the three- and six-month forecasts of $133.71 and $162.22, respectively.

Fading downside price momentum according to the Moving Average Convergence Divergence (MACD) histogram and the recent upside trajectory of the on-balance volume (OBV) indicator supports the bullish stance.

Share performance

Share information

Share CodeGILD US
IndustryPharmaceutical, Biotechnology
Market Capital (USD)169.89
One-Year Total Return17.14%
Return Year-to-Date13.00%
Current Price (USD)137.01
52-Week High (USD)157.29
52-Week Low (USD)108.46
Financial Year EndDecember
The share price is has delivered double-digit growth in the past 12 months and in 2026, with several technical indicators guiding for further upside potential.

Consensus expectations (Bloomberg)

FY25FY26EFY27EFY28E
Headline Earnings per Share (USD)8.15-0.439.8410.52
Growth (%)-105.252.386.94
Dividend Per Share (USD)3.163.283.373.50
Growth (%)3.892.504.07
Forward PE (times)13.9313.03
Forward Dividend Yield (%)2.402.462.56
Earnings are expected to decline in FY26, driven primarily by large, one-time acquired in-process R&D (IPR&D) charges from recent acquisitions, not underlying business deterioration. However, the company is set to deliver strong double-digit earnings growth over the medium term.

Buy/sell rationale

    • The lower panel is the occurrence of the Morning Doji Star Japanese candlestick pattern for the stock - a reading of one indicates when such a pattern occurred. This indicator is a three-candle Japanese candlestick pattern that signals a potential bullish reversal at the bottom of a downtrend (see the insert).
    • The price in the accumulation phase out of the Wyckoff Price Cycle also supports a bullish case for the stock. The pattern suggests that informed investors may be gradually building positions while the stock consolidates within a defined range, supporting the bullish stance. A reduction in selling pressure, improving demand and repeated support near the lower boundary of the range indicate that available supply may be absorbed.
    • Our recommended entry range is $134 to $138, or as close as possible to $135.77 - a drop below this range would indicate a substantial change in price dynamics, giving reason to negate the trade idea.
    • Our target price is $155 representing ~14.2% upside from current levels. According to forward calculations of the Relative Strength Index (RSI) indicator, the share will be overbought at $200, making our profit target realistic.
    • Our proposed time to exit is towards mid-November 2026, but investors can adjust for a longer or shorter time horizon, depending on price behaviour.
    • A drop below $128, or 5.7% below current levels, would suggest weakening technicals, and a stop-loss is recommended at this level.
    • We expect moderate price fluctuations and suggest a medium at-risk allocation for this trade.

Fundamental view

    • Gilead Science has one operating segment which primarily focuses on the discovery, development and commercialisation of innovative medicines in areas of unmet medical need.
    • The group sells and distributes certain products through its corporate partners under collaborative agreements. Overall, HIV generates ~75% of the company's revenue, while oncology accounts for ~10%, and liver disease, Veklury, and other account for the remaining revenue.
    • Gilead Sciences has operations in more than 35 countries and generates ~75% of its revenue in the United States, while about 15% comes from Europe, and over 10% comes from other countries.
    • The company's products on the market include AmBisome, a proprietary liposomal formulation of amphotericin B, an antifungal agent, for the treatment of serious invasive fungal infections caused by various fungal species in adults. Beyond HIV/AIDS, Gilead also markets Haematology and Oncology medicines and the Yescarta CAR-T cell therapy for cancer.
    • The group relies on several collaborative relationships with third parties for its sales and marketing performance in certain territories. In some countries, the company relies on international distributors for the sale of some of its products.
    • In 2Q26, base business sales increased 10% year-on-year to $7.6 billion, due to solid demand which was primarily driven by HIV products, Trodelvy and Livdelzi, and partially offset by lower Cell Therapy and Hepatitis C Virus (HCV) products.
    • Looking ahead, management will continue to invest in the business and R&D pipeline while managing expenses and maintaining its ordinary course partnerships and business development transactions to future growth. The group maintains a solid pipeline of 53 clinical programmes and four clinical opt-in assets.
    • From a risk perspective, the company relies heavily on a few blockbuster drugs and any disruption to its core markets can significantly impact its financial health. Additionally, the company is exposed to clinical trial failures and pipeline halts due to the high risk associated with developing new drugs.

Update on previous trade ideas

Share Name and position EntryCurrent PriceMovementCommentTime to exit
VMC - Buy (Continue to hold)268.94287.79+7.0%The combination of supportive long-term trend dynamics, improving momentum conditions and favourable mean-reversion characteristics remains of interest. Remains just below its 200-day simple moving average (SMA). Fading downside momentum is supportive. Our profit target is maintained at $314.00 with a trailing stop-loss at ~$275.00.19 August 2026
SYK - Buy (Continue to hold)329.74348.15+5.6%The price at the lower range of an inclining linear regression channel pattern remains of interest. Testing its 200-day SMA. Upside momentum is supportive. Our profit target is maintained at $401.00 with a trailing stop-loss at $338.00. 14 October 2026
DD - Buy (Continue to hold)140.77144.49+2.6%The price at the start of wave 5 out of the Elliott Wave Price Theory remains of interest. Remains above its 200-day SMA. Fading downside momentum is supportive. Our profit target is maintained at $170.00 with a trailing stop-loss at $136.00. 7 October 2026
TSN - Buy (Continue to hold)58.7458.04-1.2%The price in a developing inclining channel pattern remains of interest. Remains wedged between its 200-week SMA support and its 200-day SMA resistance. Downside momentum is a concern to the trade idea. Our profit target is maintained at $69.00 with a trailing stop-loss at $55.00.7 October 2026

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